For the best organisation of work space, I have five advices
Use an wrist cushion for obtens the natural conform of the wrist.
Install an surface efficient for the mouse and reduce the unnecessary movements that cause aches in wrist and hands.
Adjust your position to avoid glare solves the problem by causing neck and shoulder aches.
Install a document holder minimize eye and neck movements by keeping your documents at the proper viewing position.
Use a chair adapted for the computer work.